Leupeptin, 100 mg

Description

Leupeptin is an organic compound produced by actinomycetes, serine and cysteine proteases reversibly. Inhibits trypsin-like proteases and some cysteine proteases including endoproteinase Lys-C, Kallikrein, papain, thrombin, cathepsin B and trypsin.
MW:426.56 s 49.04 . 18.02 {C20H36N6O4 . ½H2SO4 . H2O}
Ac-Leu-Leu-Argininal (hemi-sulfated form). Thus material has three tautomeric isomers that can be visualized by chromatography.
Appearance: White amorphous powder
Working range 10-100μM. Stable for several hours in water. Stock solutions of 10mM in water are stable for 1 week at 4ºC and 6 months at -20ºC.
5mg/1.054 mL = 10mM. Typically dilute 1:100 for a 100μM working solution.
Source: Organic isolated from actinomycetes.

Maintain dry at -20ºC for up to 18 months after date of receipt. Store reconstituted product in aliquots at -20ºC for up to 6 months. Avoid repeated thaw freeze cycles.