Streptozocin ≥75% α-anomer basis, ≥98% (HPLC) (Sigma-Aldrich)

Description:

CAS Number : 18883-66-4

Molecular weight : 265.22 g/mol

Empirical formula : C8H15N3O7

Synonyms : N-(Methylnitrosocarbamoyl)-α-D-glucosamine, Streptozotocin

Streptozocin or streptozotocin, is obtained from Streptomyces achromogenes.[1] Streptozotocin, a glucosamine-nitrosourea, is a DNA alkylating agent that enters cells exclusively via the GLUT2 glucose transport protein. Streptozocin, a diabetagen, is especially toxic to pancreatic islet insulin-producing β-cells. It is toxic to GLUT2 positive neuroendocrine tumor cells.